Researchers trace origin of blood-brain barrier 'sentry cells'
That is a picture of an grownup zebrafish mind exhibiting fluorescent granular perithelial cells (inexperienced) atop blood vessels (inexperienced). Credit score: Nationwide Institutes of Well being Nationwide Institutes of Well being researchers learning zebrafish have decided inhabitants of cells that defend the mind in opposition to illnesses and dangerous substances should not immune cells, as had beforehand been thought, however as a substitute probably come up from the liner of the circulatory system. This fundamental science discovering might have implications for understanding age-related decline in mind functioning and the way HIV infects mind cells. The examine, showing on-line in eLife , was performed by researchers at NIH's Eunice Kennedy Shriver Nationwide Institute of Little one Well being and Human Improvement (NICHD) and Nationwide Human Genome Analysis Institute and the Japanese Nationwide Institute of Genetics. The blood-brain barrier is ...